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  • A comparative framework for understanding the biological principles of adult neurogenesis

    A comparative framework for understanding the biological principles of adult neurogenesis

    [vc_row][vc_column][ultimate_spacer height=”35″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_custom_heading text=”PROGRESS IN NEUROBIOLOGY” font_container=”tag:p|text_align:left|line_height:1.3em” google_fonts=”font_family:Muli%3A300%2C300italic%2Cregular%2Citalic|font_style:400%20regular%3A400%3Anormal” css_animation=”slideInLeft”][ultimate_spacer height=”10″ height_on_tabs=”10″ height_on_tabs_portrait=”10″ height_on_mob_landscape=”10″ height_on_mob=”10″][vc_custom_heading text=”A comparative framework for understanding the biological principles of adult neurogenesis” font_container=”tag:h3|text_align:left|line_height:1.3em” google_fonts=”font_family:Muli%3A300%2C300italic%2Cregular%2Citalic|font_style:400%20regular%3A400%3Anormal” css_animation=”slideInLeft”][ultimate_spacer height=”10″ height_on_tabs=”10″ height_on_tabs_portrait=”10″ height_on_mob_landscape=”10″ height_on_mob=”10″][vc_column_text]Benjamin W Lindsey and Vincent Tropepe [/vc_column_text][ultimate_spacer height=”25″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_column_text]Adult neurogenesis appears to be a somewhat extreme and uneconomical form of structural remodeling, compared to the relatively subtle modifications in synaptic morphology that is known to mediate functional plasticity of neural circuitry. Nonetheless, it is precisely this attribute of adult neurogenesis that is beginning to redefine contemporary notions of neural plasticity. Thus, it is no surprise that the field of adult neurogenesis has in the last few decades become one of the most research-intensive fields in the neurosciences. However, despite the impressive progress made on delineating the molecular and cellular properties underlying the process of adult neurogenesis in a few laboratory models, we know very little about the anatomical organization, species diversity, functional significance and evolutionary history of this trait. The importance of understanding the basic cell biology of adult neurogenesis is paramount, but without considering how the natural environment regulates neurogenesis and how this trait has evolved, our understanding remains incomplete. Our current knowledge of adult neurogenesis rests on studies of no more than a few dozen species worldwide, and only a small subset of these species has undergone detailed anatomical mapping for the presence of this trait (Fig. 1). Considering that the animal kingdom consists of approximately 1.5 million known species, this represents a very tiny sampling of the potential diversity of adult neurogenesis.[/vc_column_text][ultimate_spacer height=”25″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_column_text]READ FULL PUBLICATION

    Lindsey and Tropepe, 2006 (1.5 MB)

    [/vc_column_text][ultimate_spacer height=”25″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_btn title=”back to publications” color=”orange” i_icon_fontawesome=”fa fa-bookmark-o” add_icon=”true” link=”url:http%3A%2F%2Flindseylab.ca%2Fpublications%2F|title:PUBLICATIONS%202||”][ultimate_spacer height=”25″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][/vc_column][/vc_row]

  • Testing the use of visual cues of a monocular predator, the veiled chameleon (Chamaeleo calyptratus) during prey selection

    [vc_row][vc_column][ultimate_spacer height=”35″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_custom_heading text=”RUSSIAN JOURNAL OF HERPETOLOGY” font_container=”tag:p|text_align:left|line_height:1.3em” google_fonts=”font_family:Muli%3A300%2C300italic%2Cregular%2Citalic|font_style:400%20regular%3A400%3Anormal” css_animation=”slideInLeft”][ultimate_spacer height=”10″ height_on_tabs=”10″ height_on_tabs_portrait=”10″ height_on_mob_landscape=”10″ height_on_mob=”10″][vc_custom_heading text=”Testing the use of visual cues of a monocular predator, the veiled chameleon (Chamaeleo calyptratus) during prey selection” font_container=”tag:h3|text_align:left|line_height:1.3em” google_fonts=”font_family:Muli%3A300%2C300italic%2Cregular%2Citalic|font_style:400%20regular%3A400%3Anormal” css_animation=”slideInLeft”][ultimate_spacer height=”10″ height_on_tabs=”10″ height_on_tabs_portrait=”10″ height_on_mob_landscape=”10″ height_on_mob=”10″][vc_column_text]Benjamin W Lindsey, and Jinzhong Fu[/vc_column_text][ultimate_spacer height=”25″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_column_text]During foraging, animals often feed selectively and choose to pursue or ignore a prey item based on a specific set of pre-determined criteria (Shine and Sun, 2003). Lizards are no exception to this rule, and at present continue to gain popularity for their use as model organisms in ecological studies (Shafir and Roughgarden, 1998). Although chemoreception has been implicated in some species (Cooper, 2000; Kaufman et al., 1996), well developed visual systems remain essential for accurate prey recognition during foraging (Janzen et al., 1995). Attempts to isolate which discriminatory cues are correlated with prey selection are restricted to only a few recent studies (Kaufman et al., 1996; Diaz and Carrascal, 1993). As with other visual predators, the underlying assumption is that lizards should utilize a combination of fundamental visual cues including prey movement, color, size, and shape to discriminate between equally accessible prey items (Ibrahim and Huntingford, 1989).

    Chameleons (family Chamaeleonidae) are excellent model systems for studying prey choice behavior for two reasons. First, they are unique for being the only terrestrial vertebrates that forage using monocular vision and independent lateral eye movement. Second, these animals possess lateral eye movement over a total range of 180° horizontally and 90° vertically (Haker et al., 2003). By switching between saccadic eye movements in the left and right eyes, these animals are able to detect prey in two separate visual fields (Pettigrew et al., 1999). This is of great benefit during prey choice experiments as prey can be introduced simultaneously into each visual field. This also provides advantages for sit-and-wait foragers such as chameleons, since they draw little attention to themselves by maintaining their head in a stationary position during prey detection.[/vc_column_text][ultimate_spacer height=”25″ height_on_tabs=”25″ height_on_tabs_portrait=”25″ height_on_mob_landscape=”25″ height_on_mob=”25″][vc_column_text]READ FULL PUBLICATION

    Lindsey and Fu, 2005 (58 KB)

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